The menu at Two Sisters Creole Kitchen showcases beloved Creole dishes. Savory seafood platters feature items like the Mega Seafood Platter and whole seafood options. Pasta lovers can enjoy shrimp and chicken linguine, cooked al dente with rich flavors.
Appetizers like stuffed jalapenos set the stage for hearty main courses. The friendly environment welcomes diners for lunch and dinner, offering delicious desserts at the end of each meal. Each dish reflects a dedication to quality and tradition.
Featured Dishes

Catfish Stella

Pecan Pie

Fried Green Tomatoes

Cobbler

Cornbread

Mega Seafood Platter

Chicken Parmesan

Fried Catfish PO-Boys

Hot and Sour Soup

Grilled Chicken Stir Fry

White Beans and Rice

Side Fried Fish

Shrimp and Fries

Small Seafood Platter

Blackened Shrimp Stella

Cheese Grits

Baked Beans

Pot Roast

Hot Sausage Poboy

Red Beans and Rice with Fried Catfish
Welcome to Two Sisters Creole Kitchen, a beloved family restaurant in Picayune, MS, established in 1997. Dive into our vibrant, festive atmosphere while savoring a delicious array of Creole and Cajun specialties, including fresh seafood, gumbo, jambalaya, and flavorful po'boys. With fast service and a menu perfect for lunch or dinner, we cater to groups and solo diners alike. Enjoy our convenient amenities like contactless delivery and takeout, alongside accessible seating for all. Experience the heart of Creole cuisine in a cozy setting that beckons tourists and locals alike to create lasting memories.